Platelet Aggregation Line

Platelet function testing by Light Transmission Aggregometry (LTA) was introduced in 1962 by Born and O’Brien. This assay remains the gold standard.

Image to download the Platelet Aggregation Line brochure
Light Transmission Aggregometry 

Employing Light Transmission Aggregometry (LTA), platelet aggregation is evaluated by measuring changes in light transmission after addition of platelet agonists to PRP (Platelet Rich Plasma). 

: Employing Light Transmission Aggregometry (LTA), recognized as the gold standard since 1962, the new TA 4-V3 or TA 8-V3 Thrombo-Aggregometer by Stago evaluates changes in light transmission after addition of platelet agonists to PRP (Platelet Rich Plasma).

 

Platelet aggregometry with LTA is indicated in different clinical situations : 

  • to diagnose platelet function defects predisposing patients to bleeding symptoms
  • to control platelet concentrates prepared for transfusion 
  • to document the effects of antiplatelet drug treatment. 

The new TA 4-V3 or TA 8-V3 Thrombo-Aggregometer by Stago, is indicated to diagnose platelet function defects predisposing patients to bleeding symptoms like Glanzmann’s thrombocytopenia, Bernard Soulier syndrome, GP VI deficiency or storage pool disease.  The new TA 4-V3 or TA 8-V3 Thrombo-Aggregometer by Stago, is indicated to document the effects of antiplatelet drug treatment like P2Y12 receptors inhibitors, Thromboxane A2 pathway inhibitors or dual treatment.

 

LTA can also be used for VWD investigation using RIPA test or confirmation of HIT. 

The new TA 4-V3 or TA 8-V3 Thrombo-Aggregometer by Stago, can be used for Von Willebrand Disease (VWD) investigation via Ristocetin Induced Platelet Aggregation test (RIPA).

 


Platelet function testing in clinical practice

Presentation of the diagnostic algorithm for bleeding related to platelet disorders developed by the SSC of the ISTH in 2015.
Diagnostic algorithm for bleeding related to platelet disorders (Gresele P, Harrison P, Gachet C, Hayward CPM, Kenny D, Mezzano D, Mumford AD, Nugent D, Nurden AT, Cattaneo M. Diagnosis of inherited platelet function disorders: guidance from the SSC of the ISTH. J. Thromb Haemost 2015; 13 (2): 314 -322.)

 

The Thrombo-Aggregometer 

A comprehensive offer that makes platelet function testing easier!

 

Image of the new TA 4-V3 or TA 8-V3 Thrombo-Aggregometer by Stago which can be used in the: Diagnosis of Platelet function disorders, Confirmation of HIT, Monitoring of anti-platelet drugs and Identification of Von Willebrand Disease via Ristocetin Induced Platelet Aggregation (RIPA).

 

Using the gold standard technology – Light Transmission Aggregometry (LTA) – for the diagnosis of a wide variety of acquired and inherited platelet disorders, the TA 4-V3 or TA 8-V3 Thrombo-Aggregometer is a valuable choice for first-line Platelet Function Disorders exploration. 

 

 

With less plasmas rejected thanks to the infrared wavelength used, time savings with up to 8 patients in parallel, an intuitive software andStago offers 6 reagents for use on the the new TA 4-V3 or TA 8-V3 Thrombo-Aggregometer : Arachidonic Acid, Collagen, ADP, TRAP-6, Epinephrin and ristocetin. an easy-to-use panel of IVD and validated agonists, the TA 4-V3 or
TA 8-V3 is a valuable choice for productivity.

Real-time recording, reagent traceability and patient history make the TA 4-V3 or TA 8-V3 a valuable choice for reliability. 

 

The TA 4-V3 or TA 8-V3 is the choice of simplicity with the remote connection, to visualise, analyse, comment, save and export patient results remotely. 

The TA 4-V3 or TA 8-V3 is the choice of simplicity with the remote connection, to visualise, analyse, comment, save and export patient results remotely.

 

To learn more about Platelet Function testing

Image to download the Platelet Aggregation Line brochure